The Human Immune Monitoring Core (HIMC) at Columbia University Irving Medical Center (CUIMC) is seeking a highly motivated and talented technician to join our team. The HIMC is an innovation-oriented high-tech service center with state-of-the-art instrumentation for advanced immunology studies. Technologies include CyTOF (high-parametric cytometry by time-of-flight), multiplexed tissue imaging (Vectra and CyCIF), multi-modal single-cell sequencing and immune profiling (10x Genomics), and other platforms. We collaborate closely with renowned scientists and physicians across multiple departments at CUIMC spanning research in cancers, cancer therapy, immunology, autoimmunity, transplantation, inflammation, infectious diseases, neuroscience, aging, and various aspects of technology development.
Key responsibilities include operation, maintenance, and troubleshooting of advanced cytometry and imaging instruments; preparation of samples and reagents; and assistance in assay development and optimization.
Operate and maintain the CyTOF, Vectra, and other next-gen cytometry, imaging, and sequencing instruments.
Prepare and manage reagents. Perform reagent validation, titration, and QC. Prepare samples and slides for analysis. Prepare sequencing libraries.
Maintain a detailed, up-to-date, and accurate record of samples, reagents, and instrument tuning, and QC. Maintain and organize the inventory. Place orders. Prepare service bills.
Perform routine data processing and data QC tasks and assist with data analysis.
Assist in the development of new assays, methods, and reagents.
Contribute to building a culture that embraces scientific excellence, integrity, efficiency, teamwork, and continuous learning and improvement.
Bachelor's degree in biological sciences, engineering, chemistry, physics, math, computer sciences, or related fields.
Prior experience with cytometry or tissue imaging is preferred but not required, as training will be provided; however, ideal candidates will be quick learners and comfortable with new technologies and have excellent hands-on and organizational skills.
Programming with R or Python.
Advanced Excel or Google Sheets.
Familiarity and excellent skills with PCR and sterile culture techniques.
Attention to detail and quality.
Skills for problem identification and troubleshooting.
Sense of ownership for the samples handled and tasks assigned.
Skills for effective and timely communication with users and colleagues.
A minimum of a 2-year commitment.
Equal Opportunity Employer / Disability / Veteran
Columbia University is committed to the hiring of qualified local residents.
Internal Number: 513011
About Columbia University
Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.